A cientista renomada Ying Xu, PhD na Universidade Buffalo, EUA, disse recentemente em uma entrevista, sobre o resveratrol, componente presente no vinho tinto:
“O resveratrol pode ser uma alternativa eficaz aos medicamentos para o tratamento de pacientes que sofrem de depressão e transtornos de ansiedade”, explicou Ying Xu, PhD, autor co-principal e professora associada de pesquisa na Faculdade UB de Farmácia e Ciências Farmacêuticas. "
Abaixo, segue o seu currículo:
Professional Summary:
I have a broad background in neuroscience and pharmacology, with specific training and expertise in behavioral, neurochemical and neurobiological analyses in animal models related to neuropsychiatric disorders, such as depression, anxiety and neuropathic pain. My research includes investigation of CNS functional roles of natural polyphenols (curcumin, resveratrol and ferulic acid) and the selective phosphodiesterases (PDEs) inhibitors (PDE2, 4 and 5) for treatment of stress-related neuropsychiatric and neurodegenerative disorders, in the mediation of the above diseases and the involved intracellular mechanisms. As PI or co-Investigator on the institutional- and NIH funded grants, I laid the groundwork for the proposed research by assessing the roles of PDE in stress-induced depression, anxiety and memory impairment in aspects of behavior and molecular biology. Recently, my project focused on investigating the predictive factors relevant to stress-induced depression and neuropathic pain, as well as the signal pathway.
Education and Training:
- Postdoctoral Fellow, Behavioral Medicine & Psychiatry, West Virginia University (2013)
- Postdoctoral Fellow, Biomedical Engineering, University of Florida (2008)
- PhD, Neuropharmacology, Peking University (2006)
- MS, Neuropharmacology, Nanjing Medical University (2001)
- MD, Xuzhou Medical College (1989)
Employment:
- Research Associate Professor, Department of Pharmaceutical Sciences, The State University of New York at Buffalo, School of Pharmacy & Pharmaceutical Sciences (2019-present)
- Research Assistant Professor, Pharmaceutical Sciences, State University of New York at Buffalo, School of Pharmacy and Pharmaceutical Sciences (2013-present)
- Research Assistant Professor, Pharmaceutical Sciences, State University of New York at Buffalo (2013-present)
- Assistant Professor, Behavioral Medicine and Psychiatry, West Virginia University, School of Medicine (2013–2014)
Awards and Honors:
- Winter Conference on Brain Research Travel Award (2015)
- American Association of College of Pharmacy New Investigator Award (2014)
- Top Reviewer Award of Elsevier Pharmacology Journals (2010)
Professional Memberships:
- Ad-hoc Journal Reviewer Editor; Frontiers in Systems Biology; Acta Neuropharmacology
- Ad-hoc Journal Reviewer; CNS Neuroscience & Therapeutics. European Journal of Pharmacology; European Neuropsychopharmacology; Experimental Neurology; International Journal of Pharmaceutical Research; Journal of Ethnopharmacology; Journal of Neurochemistry; Journal of Pharmacology and Experimental Therapeutics (JPET); Journal of Pharmacy and Pharmacology; Metabolic Brain Disease; Neurochemical Research; Neurological Research; Pharmacology, Biochemistry & Behavior; PLoS One; Progress in Neuro-Psychopharmacology & Biological Psychiatry; Scientia Pharmaceutica; Stress;
Presentations:
- "Reversal of NADPH oxidase mediated depression- and anxiety-like behaviors by inhibition of phosphodiesterase 2." Winter Conference on Brain Research, Society for Neuroscience, Phosphosdiesterase inhibitors and CNS disease (2015)
- "Inhibition of Phosphodiesterase 2 reverses stress-induced mood disorders: involvement of NADPH oxidase function." Society for Neuroscience 45th Annual Meeting, Society for Neuroscience, Emotional disease (2014)
- "The phosphodiesterase-4 inhibitor rolipram reverses alcohol withdrawal-induced anxiety-like behavior in mice and rats" Research Society on Alcoholism (RSA) 37th Annual Scientific Meeting, Research Society on Alcoholism, Research Society on Alcoholism (2014)
- "Role of PDE2 in stress-induced impairment of cognition and neural remodeling" Behavioral Pharmacology conference, Behavioral Pharmacology Society, Behavioral Pharmacology Section (2014)
- "Role of phosphodiesterase-4 (PDE4) in anxiety" Experimental Biology conference, Pharmacology and experimental therapeutics, Behavioral Pharmacology Section (2014)
- "Inhibition of phosphodiesterase 2 reverses behavioral and synaptic deficits caused by chronic stress exposure" (2012)
- "Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavior changes via cGMP/PKG dependent pathway" Neuroscience 42th Annual Meeting (2011)
Service Activities:
- Judge for Graduate Student Best Abstract Award; Ad Hoc Reviewer (2014–present)
- Ad-hoc Journal Reviewer Editor; Board Member (2009–present)
- Ad-hoc Journal Reviewer; Peer Reviewer (2006–present)
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